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Terahertz (THz) light is special since many
materials like plastics and ceramics are transparent whereas many
biomolecules have distinct spectral signatures or fingerprints. THz
imaging is considered as a new tool in security screening at airports
since clothing, plastic bags are transparent while drugs and metal
objects are detectable.
My interest in exploring THz imaging is to
...
- detect nano-concentrations of
biomolecules like
proteins (see image: the total amount of aminoacids is 63 µg
within a circle of 6 mm diameter. A single pixel on the sub-mm scale
corresponds to 3 nmol per pixel. For details see E. Bründermann et al., Applications of
semiconductor terahertz lasers in biomolecular spectroscopy and imaging, Proc. SPIE 6194, 619406 (2006) - Conference 6194: Millimeter-Wave and
Terahertz Photonics, Strasbourg, April 6, 2006 (invited)
- Link to pdf at SPIE).
- separate different biomolecules by
correlating
THz fingerprints with their structure
A THz image involves scanning a laser beam
across
a sample. Array detectors typically suffer from the fact that they are
not sensitive enough or extremely expensive.
However, our powerful unique THz laser allows to take an image
in a single laser pulse onto
a normal array. This means THz imaging might get as easy as taking a
photograph with a digital camera in the future.
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