Terahertz Imaging - Terahertz Bildgebung

 
 
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Terahertz (THz) light is special since many materials like plastics and ceramics are transparent whereas many biomolecules have distinct spectral signatures or fingerprints. THz imaging is considered as a new tool in security screening at airports since clothing, plastic bags are transparent while drugs and metal objects are detectable.

My interest in exploring THz imaging is to ...

  • detect nano-concentrations of biomolecules like proteins (see image: the total amount of aminoacids is 63 µg within a circle of 6 mm diameter. A single pixel on the sub-mm scale corresponds to 3 nmol per pixel. For details see E. Bründermann et al., Applications of semiconductor terahertz lasers in biomolecular spectroscopy and imaging, Proc. SPIE 6194, 619406 (2006) - Conference 6194: Millimeter-Wave and Terahertz Photonics, Strasbourg, April 6, 2006 (invited) - Link to pdf at SPIE).
  • separate different biomolecules by correlating THz fingerprints with their structure

A THz image involves scanning a laser beam across a sample. Array detectors typically suffer from the fact that they are not sensitive enough or extremely expensive. However, our powerful unique THz laser allows to take an image in a single laser pulse onto a normal array. This means THz imaging might get as easy as taking a photograph with a digital camera in the future.

drops of aminoacids measured within 4 microseconds

Examples of THz images taken with the germanium THz laser

2.4 THz image of hologram in bank note THz scan of a bank note hologram at 2.4 THz and a razor blade behind paper. Photo of the razor blade on paper from the metal side. Paper absorbs only a little bit of THz light. razor blade on paper from the blade side THz image razor blade behind paper
THz-drops The THz image shows several lactalbumin hydrolysate drops with different concentrations. The minimum detectable dosage lies in the range of nanograms and nanomol's. Each image pixel has been illuminated with just "one" laser pulse of a few microseconds length to illustrate a single snap-shot. Part of this research, initiated by D.R. Chamberlin, is supported by Agilent Technologies, San Jose. We have reconstructed the company logo from lactalbumin hydrolysate drops and we took a THz image of it. agilent
Erik Bründermann collaborates with the optoelectronics-group in engineering at RUB. More information? ... see my general review "Chemistry and medicine in a new light. Science and fiction with terahertz light." published in CLB Chemie in Labor und Biotechnik (2004), 55(2), 56-60 (in german).
 
 
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